SKAT - SNP-Set (Sequence) Kernel Association Test
Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values.
Last updated 9 days ago
sequencecpp
9.58 score 45 stars 16 dependents 268 scripts 1.3k downloadsMetaSKAT - Meta Analysis for SNP-Set (Sequence) Kernel Association Test
Functions for Meta-analysis Burden Test, Sequence Kernel Association Test (SKAT) and Optimal SKAT (SKAT-O) by Lee et al. (2013) <doi:10.1016/j.ajhg.2013.05.010>. These methods use summary-level score statistics to carry out gene-based meta-analysis for rare variants.
Last updated 5 months ago
cpp
2.30 score 1 stars 20 scripts 355 downloadsdSVA - Direct Surrogate Variable Analysis
Functions for direct surrogate variable analysis, which can identify hidden factors in high-dimensional biomedical data.
Last updated 8 years ago
1.00 score 5 scripts 157 downloads