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SKAT - SNP-Set (Sequence) Kernel Association Test
Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values.
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sequencecpp
9.88 score 54 stars 13 dependents 358 scripts 915 downloadsMetaSKAT - Meta Analysis for SNP-Set (Sequence) Kernel Association Test
Functions for Meta-analysis Burden Test, Sequence Kernel Association Test (SKAT) and Optimal SKAT (SKAT-O) by Lee et al. (2013) <doi:10.1016/j.ajhg.2013.05.010>. These methods use summary-level score statistics to carry out gene-based meta-analysis for rare variants.
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cpp
2.38 score 1 stars 24 scripts 333 downloadsdSVA - Direct Surrogate Variable Analysis
Functions for direct surrogate variable analysis, which can identify hidden factors in high-dimensional biomedical data.
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1.00 score 5 scripts 170 downloads